FXR agonist 12

CAT: 0931-T205709-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T205709-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1831862-88-4

Target

FXR

Related Pathways

Metabolism

Bioactivity

FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.

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C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)[C@H](CC)[C@@]1(CCCC2)[H])[H])[H]

Molecular Formula

C26H44O3

Molecular Weight

404.626

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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FXR agonist 12

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