FXR agonist 11

• CAS Number :

  2768502-17-4

• Target :

  FXR

• Related Pathways :

  Metabolism

• Bioactivity :

  FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 ?M and a maximal effect of 73.7%. It significantly increases GSH levels in the liver and is used to study drug-induced liver injury.

• Smiles :

  O=C(O)C=1C=CC=C(C1)NC(=O)COC2=CC=C3C(=C2)NC(=O)CC3

• Molecular Formula :

  C18H16N2O5

• Molecular Weight :

  340.33

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C