FXR agonist 3

CAT: 0931-T74996-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T74996-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

FXR, Others

Related Pathways

Metabolism, Others

Purity

0.9504

Bioactivity

FXR agonist 3 is an anti-NASH compound with antifibrotic and anti-fibrotic activity, inhibiting the expression of COL1A1, TGF-β1, α-SMA, and TIMP1, with an IC50 value of 8.19 μmol/L for COL1A1. FXR agonist 3 ameliorates CDAHFD and BDL-induced liver injury in vivo by activating FXR.

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COC1=CC2=C(C=C1OC)CC[N+]3=C2C=C4C(C(OCC5=CC=CC(C)=C5)=C(OC)C=C4)=C3.[Br-]

Molecular Formula

C28H28BrNO4

Molecular Weight

521.12

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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FXR agonist 3

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