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BRD4 degrader-5

CAT: 0931-T205597-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205597-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Autophagy, AUTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic, Autophagy
Bioactivity
BRD4 degrader-5 (Compound 23) is a protein degrader utilizing a hydrophobic tag (HyTag) that targets BRD4 for degradation through endoplasmic reticulum stress and the autophagy-lysosome pathway (DC50 = 24.7 μM) . It also inhibits the proliferation of 4T1 cancer cells, with an IC50 of 20.6 μM.
Molecular Formula
C35H42ClN7O2S
Molecular Weight
660.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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