BRD4 degrader-5

CAT: 0931-MF-0113960-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0113960-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Autophagy|||AUTACs|||Epigenetic Reader Domain
Related Pathways
PROTAC|||Chromatin/Epigenetic|||Autophagy
Bioactivity
BRD4 degrader-5 (Compound 23) is a protein degrader utilizing a hydrophobic tag (HyTag) that targets BRD4 for degradation through endoplasmic reticulum stress and the autophagy-lysosome pathway (DC50 = 24.7 ?M) . It also inhibits the proliferation of 4T1 cancer cells, with an IC50 of 20.6 ?M.
Molecular Formula
C35H42ClN7O2S
Molecular Weight
660.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products