BRD4 degrader AT1

CAT: 0931-T5439Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T5439Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2098836-45-2

Target

PROTACs, Epigenetic Reader Domain

Related Pathways

PROTAC, Chromatin/Epigenetic

Bioactivity

BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells.

Smiles

CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCCCCCSC(C)(C)[C@@H](C(=O)N4C[C@@H](C[C@H]4C(=O)NCC5=CC=C(C=C5)C6=C(N=CS6)C)O)NC(=O)C)C7=CC=C(C=C7)Cl)C

Molecular Formula

C48H58ClN9O5S3

Molecular Weight

972.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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