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SHP1 activator 1

CAT: 0931-T205309-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205309-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Phosphatase, Apoptosis, STAT
Related Pathways
JAK/STAT signaling, Apoptosis, Stem Cells, Metabolism
Bioactivity
SHP1 activator 1 (Compound 3n) is an activator of protein tyrosine phosphatase 1 containing the src homology-2 domain (SHP1), with an EC50 of 17.66 μM. It inhibits the proliferation of ABC-DLBCL cells and induces apoptosis by suppressing the STAT3 signaling pathway. In MDA-MB-231 cells, SHP1 activator 1 emits blue and green fluorescent signals, making it suitable as a cellular imaging agent.
Molecular Formula
C27H34N4O4
Molecular Weight
478.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C