MTH1 activator-1

• Target:

  DNA/RNA Synthesis

• Related Pathways:

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Bioactivity:

  MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.

• Smiles:

  O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCOCC2)C3=NC=C(C#CC4=CC=CC=5C=NC=CC45)C=C3

• Molecular Formula:

  C29H23F3N4O2

• Molecular Weight:

  516.514

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2803422-60-6