HNC-1664

• Target:

  Anti-infection|||SARS-CoV|||DNA/RNA Synthesis|||Virus Protease

• Related Pathways:

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology

• Bioactivity:

  HNC-1664 is an orally active inhibitor of RNA-dependent RNA polymerase (RdRP) . It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 wild type and its variants (XBB.1.18, HK.3.1, BF.7.14, BA.1, HCoV-229E, HCoV-OC43), as well as arenaviruses. HNC-1664 also demonstrates anti-infective efficacy in a mouse model infected with the SARS-CoV-2 Delta variant.

• Smiles:

  F[C@@H]1[C@H](N2C=3C(C(I)=C2)=C(C)N=CN3)O[C@H](CO)[C@H]1O

• Molecular Formula:

  C12H13FIN3O3

• Molecular Weight:

  393.153

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2127358-36-3