R-1663

• CAS Number :

  865451-66-7

• Target :

  Others|||Endogenous Metabolite

• Related Pathways :

  Metabolism|||Others

• Bioactivity :

  R-1663 is a factor Xa inhibitor. R-1663 prolonged clotting times, inhibited thrombin generation (peak height and endogenous thrombin potential [ETP]) and anti-factor Xa activity in a concentration-dependent manner without increasing bleeding time. Pharmacodynamic parameters were strongly correlated to R-1663 plasma concentrations. The inhibition was more pronounced on peak height (IC?? = 194 ng/ml) than on ETP (2790 ng/ml) .

• Smiles :

  C(NC1=C(F)C=C(C=C1)N2C(=O)C=CC=C2)(=O)[C@@H]3[C@@H](C(NC4=CC=C(Cl)C=N4)=O)CN(CC(F)F)C3

• Molecular Formula :

  C24H21ClF3N5O3

• Molecular Weight :

  519.9

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C