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R-1663

CAT: 0931-T28491-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T28491-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
865451-66-7
Target
Others|||Endogenous Metabolite
Related Pathways
Metabolism|||Others
Bioactivity
R-1663 is a factor Xa inhibitor. R-1663 prolonged clotting times, inhibited thrombin generation (peak height and endogenous thrombin potential [ETP]) and anti-factor Xa activity in a concentration-dependent manner without increasing bleeding time. Pharmacodynamic parameters were strongly correlated to R-1663 plasma concentrations. The inhibition was more pronounced on peak height (IC?? = 194 ng/ml) than on ETP (2790 ng/ml) .
Smiles
C(NC1=C(F)C=C(C=C1)N2C(=O)C=CC=C2)(=O)[C@@H]3[C@@H](C(NC4=CC=C(Cl)C=N4)=O)CN(CC(F)F)C3
Molecular Formula
C24H21ClF3N5O3
Molecular Weight
519.9
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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