KF-52

• Target :

  Phosphatase

• Related Pathways :

  Metabolism

• Bioactivity :

  KF-52 is an inhibitor of phosphofructokinase-1 (PFK1), possessing an IC50 value of 2.1 ?M. It significantly enhances the ratio of oxygen consumption rate (OCR) to extracellular acidification rate (ECAR) .

• Smiles :

  C1CN([C@@H](C2=C1C3=CC=CC=C3N2)C(F)(F)F)C(=O)[C@@H]4[C@H]5C[C@@H]([C@@H]4C(=O)O)C=C5

• Molecular Formula :

  C21H19F3N2O3

• Molecular Weight :

  404.382

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C