PRMT5-IN-47

• Target :

  Histone Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  PRMT5-IN-47 (compound 20) is a potent, selective, and orally active MTA co-operative PRMT5 inhibitor, with an IC50 value of 15 nM. It exhibits antiproliferative and anticancer activity.

• Smiles :

  C(N(C)[C@H]1CN(CC1)C2=CC=C(C#N)C=C2)(=O)C=3C=C4C5=C(C(N)=NC4=CC3F)COC5

• Molecular Formula :

  C24H22FN5O2

• Molecular Weight :

  431.462

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3065081-87-7