PRMT5-IN-47

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  PRMT5-IN-47 (compound 20) is a potent, selective, and orally active MTA co-operative PRMT5 inhibitor, with an IC50 value of 15 nM. It exhibits antiproliferative and anticancer activity.

• Smiles:

  C (N (C) [C@H]1CN (CC1) C2=CC=C (C#N) C=C2) (=O) C=3C=C4C5=C (C (N) =NC4=CC3F) COC5

• Molecular Formula:

  C24H22FN5O2

• Molecular Weight:

  431.462

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3065081-87-7