MAT2A-IN-21

• Target:

  Methionine Adenosyltransferase (MAT)

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  MAT2A-IN-21 (compound 28) is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A), with an IC50 of 49 nM. It selectively inhibits cancer cells with MTAP deficiency.

• Smiles:

  O=C1C(=NC=2C=CC(=CC2N1C3=CC=C(OC(F)F)C=C3)C4CC4)C=5C=CC=6N=CN(C6C5)C

• Molecular Formula:

  C26H20F2N4O2

• Molecular Weight:

  458.459

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3062073-94-0