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RU-0415529

CAT: 0931-T204295-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204295-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1358734-35-6
Target
SARS-CoV, DNA Methyltransferase
Related Pathways
Chromatin/Epigenetic, Microbiology/Virology
Bioactivity
RU-0415529 is an orally active inhibitor of SARS-CoV-2 non-structural protein 14 (NSP14), with an IC50 of 356 nM. It inhibits viral RNA methylation and replication by stabilizing the cap-binding pocket through SAH binding. Additionally, RU-0415529 exhibits anti-infective activity in mouse models.
Smiles
O=C(NCC=1C=CC=CC1OC)C2=CC(=C(N2C)C)S(=O)(=O)N3CCC(C)CC3
Molecular Formula
C21H29N3O4S
Molecular Weight
419.538
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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