RU-0415529

• Target:

  SARS-CoV|||DNA Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic|||Microbiology/Virology

• Bioactivity:

  RU-0415529 is an orally active inhibitor of SARS-CoV-2 non-structural protein 14 (NSP14), with an IC50 of 356 nM. It inhibits viral RNA methylation and replication by stabilizing the cap-binding pocket through SAH binding. Additionally, RU-0415529 exhibits anti-infective activity in mouse models.

• Smiles:

  O=C(NCC=1C=CC=CC1OC)C2=CC(=C(N2C)C)S(=O)(=O)N3CCC(C)CC3

• Molecular Formula:

  C21H29N3O4S

• Molecular Weight:

  419.538

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1358734-35-6