NZ-804

CAT: 0931-MF-0112429-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0112429-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2858658-44-1
Target
SARS-CoV|||Virus Protease
Related Pathways
Microbiology/Virology
Bioactivity
NZ-804 is an orally active inhibitor of the SARS-CoV-2 main protease (Mpro) with an IC50 of 8.9 nM. It inhibits replication of SARS-CoV-2 in HeLa-hACE2 cells, showing an EC50 of 14 nM. NZ-804 exhibits broad-spectrum antiviral activity against various CoVs and decreases viral replication in mice and hamster models.
Smiles
O=C(C1=CN=CC=2C=CNC21)N3CCC(=C4C=5C=CC=CC5CS(=O)(=O)C=6C=CC=CC64)CC3
Molecular Formula
C27H23N3O3S
Molecular Weight
469.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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