NZ-804

• Target :

  SARS-CoV|||Virus Protease

• Related Pathways :

  Microbiology/Virology

• Bioactivity :

  NZ-804 is an orally active inhibitor of the SARS-CoV-2 main protease (Mpro) with an IC50 of 8.9 nM. It inhibits replication of SARS-CoV-2 in HeLa-hACE2 cells, showing an EC50 of 14 nM. NZ-804 exhibits broad-spectrum antiviral activity against various CoVs and decreases viral replication in mice and hamster models.

• Smiles :

  O=C(C1=CN=CC=2C=CNC21)N3CCC(=C4C=5C=CC=CC5CS(=O)(=O)C=6C=CC=CC64)CC3

• Molecular Formula :

  C27H23N3O3S

• Molecular Weight :

  469.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2858658-44-1