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STAT3-IN-39

CAT: 0931-T203317-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203317-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3037596-35-0
Target
STAT
Related Pathways
JAK/STAT signaling, Stem Cells
Bioactivity
STAT3-IN-39 (compound 10K) is an orally active inhibitor of STAT3, demonstrating effective inhibition of STAT3 phosphorylation with an IC50 of 0.47 μM in NIH-3T3 cells. It hinders TGF-β1-induced fibrotic responses and prevents epithelial-mesenchymal transition in A549 cells. STAT3-IN-39 is applicable for research related to idiopathic pulmonary fibrosis.
Smiles
O=C(C1=CC=2C=CC=CC2S1(=O)=O)N3CCN(CC4=CC(F)=C(F)C=C4F)CC3
Molecular Formula
C20H17F3N2O3S
Molecular Weight
422.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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