STAT3-IN-39

• Target :

  STAT

• Related Pathways :

  JAK/STAT signaling|||Stem Cells

• Bioactivity :

  STAT3-IN-39 (compound 10K) is an orally active inhibitor of STAT3, demonstrating effective inhibition of STAT3 phosphorylation with an IC50 of 0.47 ?M in NIH-3T3 cells. It hinders TGF-?1-induced fibrotic responses and prevents epithelial-mesenchymal transition in A549 cells. STAT3-IN-39 is applicable for research related to idiopathic pulmonary fibrosis.

• Smiles :

  O=C(C1=CC=2C=CC=CC2S1(=O)=O)N3CCN(CC4=CC(F)=C(F)C=C4F)CC3

• Molecular Formula :

  C20H17F3N2O3S

• Molecular Weight :

  422.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3037596-35-0