MD-265

CAT: 0931-T203203-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T203203-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2415160-21-1

Target

PROTACs, MDM-2/p53

Related Pathways

PROTAC, Apoptosis

Bioactivity

MD-265 is a PROTAC degrader that targets and degrades MDM2, leading to the activation of p53 in cancer cells with wild-type p53. MD-265 achieves complete tumor regression and enhances long-term survival in leukemic mice.

Smiles

O=C1[C@@]2(C3(N[C@@H](C(N[C@@H]4CC[C@@H](C(=O)N5CCC(C#CC6=C7C(C(=O)N(C7)C8C(=O)NC(=O)CC8)=CC=C6)CC5)CC4)=O)[C@@H]2C9=C(F)C(Cl)=CC=C9)CCCCC3)C=%10C(N1)=CC(Cl)=CC%10

Molecular Formula

C50H51Cl2FN6O6

Molecular Weight

921.88

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-169327-01	MD-265
200770	RAF-265 (CHIR-265)
HY-169948	BML-265
HY-116557	JCP-265
TRC-R072900-100MG	RAF 265
sc-492599	ML 265
E1KS1361	MgCD-265
C4181-5	ML-265
GTR19263041-01	Antibiotic AT 265
FF41064-01	MGCD 265

MD-265

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