EAPB-0503

• CAS Number :

  1140627-77-5

• Target :

  Apoptosis|||PARP|||Bcr-Abl

• Related Pathways :

  Chromatin/Epigenetic|||Angiogenesis|||Apoptosis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair

• Bioactivity :

  EAPB-0503, an imidazoquinoxaline derivative and an analog of Imiquimod, selectively reduces HDM2 expression and activates the p53 pathway in cells expressing NPM1c, thereby inducing apoptosis.

• Smiles :

  N=1C=C(C2=CC=CC(OC)=C2)N3C1C(=NC=4C=CC=CC43)NC

• Molecular Formula :

  C18H16N4O

• Molecular Weight :

  304.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C