Products for Research Use Only

EAPB-0503

CAT: 0013-GTR19241697-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241697-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EAPB-0503 is an imidazoquinoxaline analog of Imiquimod that selectively downregulates HDM2 and activates p53 in NPM1c-expressing cells, leading to apoptosis. This mechanism supports its investigation in vitro and in vivo for cancers driven by NPM1 mutations, such as acute myeloid leukemia (AML) .
CAS Number
1140627-77-5
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
N=1C=C (C2=CC=CC (OC) =C2) N3C1C (=NC=4C=CC=CC43) NC
Molecular Formula
C18H16N4O
Molecular Weight
304.35
Storage Conditions
-20°C
Notes
For research use only.

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