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EAPB 02303

CAT: 0804-HY-153384-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153384-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EAPB 02303 is a microtubule-disrupting agent and inhibitor. EAPB 02303 induces mitosis arrest and impairment of spindle assembly. Thus, EAPB 02303 induces apoptosis and exhibits antitumor activity. EAPB 02303 also exhibits a potent synergy with Paclitaxel at lower concentrations[1].
CAS Number
1958290-51-1
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin; Mitosis
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eapb-02303.html
Purity
98.05
Solubility
H2O : 30 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC(C=C1)=C(O)C=C1C2=CN=C3C(NC)=NC4=CC=CC=C4N32
Molecular Formula
C17H14N4O2
Molecular Weight
306.32
References & Citations
[1]Bigot K, et al. Imiqualines for pancreatic cancer: first-in-class potent and synergistic inhibitors of microtubule polymerisation[J]. Cancer Research, 2023, 83 (7_Supplement) : 5729-5729.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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