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PROTAC SMARCA2 degrader-29

CAT: 0931-T201541-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201541-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2865193-25-3
Target
PROTACs, Neurotensin Receptor, Epigenetic Reader Domain
Related Pathways
GPCR/G Protein, PROTAC, Chromatin/Epigenetic
Bioactivity
PROTAC SMARCA2 degrader-29 (Example 87) is a potent PROTAC SMARCA2 (BRM) degrading agent with a DC50 ranging between 10-100 nM (BRM) and over 1 μM (BRG1, also known as SMARCA2) .
Smiles
OC1=C(C=2C=C3C(C=C(S3)C4CCN(CC4)C5CCN(CC5)C=6C=C([C@H](C(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C9=C(C)N=CS9)=O)C[C@@H](O)C7)C(C)C)ON6)=NN2)C=CC=C1
Molecular Formula
C47H54N8O5S2
Molecular Weight
875.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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