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CDK-TCIP1

CAT: 0931-T201343-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201343-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3008612-35-6
Target
Bcl-2 Family, CDK
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Bioactivity
CDK-TCIP1 is a bivalent molecule that links the CDK9 inhibitor SNS-032 with the BCL6 ligand BI3812. It effectively and specifically kills cells overexpressing BCL6, with an EC50 of 7.7 nM for SUDHL5 cells.
Smiles
O=C1C(OCC(=O)NC)=CC=2C=C(C=C(OC)C2N1C)NC3=NC(=NC=C3Cl)N4CCC(C(=O)NCCCCCCC(=O)N5CCC(C(=O)NC6=NC=C(S6)SCC7=NC=C(O7)C(C)(C)C)CC5)CC4
Molecular Formula
C48H62ClN11O8S2
Molecular Weight
1020.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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