Products for Research Use Only

CDK-IN-9

CAT: 0931-T62235-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62235-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Apoptosis, DNA/RNA Synthesis, Others, CDK
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others, Apoptosis
Bioactivity
CDK-IN-9 (compound 24) is a potent inhibitor of CDK and acts on CDK2/E (IC50: 4 nM) . It functions as a molecular gel that induces interaction between CDK12 and DDB1, and can dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis.
Molecular Formula
C21H24N8S
Molecular Weight
420.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C