CDK-IN-9

• Target:

  Apoptosis|||DNA/RNA Synthesis|||Others|||CDK

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others|||Apoptosis

• Bioactivity:

  CDK-IN-9 (compound 24) is a potent inhibitor of CDK and acts on CDK2/E (IC50: 4 nM) . It functions as a molecular gel that induces interaction between CDK12 and DDB1, and can dephosphorylate retinoblastoma protein and RNA polymerase II, thereby inducing apoptosis.

• Molecular Formula:

  C21H24N8S

• Molecular Weight:

  420.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C