CDK-IN-16

• Description:

  CDK-IN-16 (Compound 5g) is a CDK2/cyclin A2 inhibitor with an IC50 of 1.67 μM. CDK-IN-16 exhibits anticancer activity. The IC50 of CDK-IN-16 against the AGS cell line is 3.5 μM[1].

• UNSPSC:

  12352005

• Target:

  CDK

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Smiles:

  OC1=CC=C(C2=C3CCC4=CC=CC=C4C3=NC(C5=CC=CN=C5)=N2)C=C1

• Molecular Formula:

  C23H17N3O

• Molecular Weight:

  351.40

• References & Citations:

  [1]Saravanakumar N, et al. Novel Fused Pyrimidines as Potent Cyclin-Dependent Kinases Inhibitor for Gastric Adenocarcinoma: Combined In Vitro, In Silico Anticancer Studies. Chem Biol Drug Des. 2024 Nov;104 (5) :e70013.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported