Bfl-1-IN-5

• Target :

  Bcl-2 Family|||Caspase

• Related Pathways :

  Proteases/Proteasome|||Apoptosis

• Bioactivity :

  Bfl-1-IN-5 (Compound (R, R, S) -26) is a selective inhibitor of Bfl-1, demonstrating an IC50 of 0.022 ?M. This compound enhances the activity of caspase-3/7, with an EC50 of 0.37 ?M, and also inhibits the viability of SU-DHL-1 cells, showing an EC50 of 1.3 ?M.

• Smiles :

  C(CNC(C)=O)[C@H]1C=2C3=C(C=CC2CC1)N=C(C)O3

• Molecular Formula :

  C24H24F3N3O2

• Molecular Weight :

  443.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C