Bfl-1-IN-5

CAT: 0931-MF-0110533-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0110533-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Bcl-2 Family|||Caspase
Related Pathways
Proteases/Proteasome|||Apoptosis
Bioactivity
Bfl-1-IN-5 (Compound (R, R, S) -26) is a selective inhibitor of Bfl-1, demonstrating an IC50 of 0.022 ?M. This compound enhances the activity of caspase-3/7, with an EC50 of 0.37 ?M, and also inhibits the viability of SU-DHL-1 cells, showing an EC50 of 1.3 ?M.
Smiles
C(CNC(C)=O)[C@H]1C=2C3=C(C=CC2CC1)N=C(C)O3
Molecular Formula
C24H24F3N3O2
Molecular Weight
443.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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