HDAC6-IN-61

CAT: 0931-T210888-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T210888-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Microtubule Associated, ERK, GPCR, HDAC

Related Pathways

Chromatin/Epigenetic, Endocrinology/Hormones, Cytoskeletal Signaling, DNA Damage/DNA Repair, MAPK, GPCR/G Protein

Bioactivity

HDAC6-IN-61 (Compound 4e) is an HDAC6 inhibitor with an IC50 of 73 nM, demonstrating greater selectivity compared to other HDAC isomers. It also acts as an activator of GPR40. HDAC6-IN-61 can increase the acetylation of tubulin and phosphorylation levels of ERK. This compound is relevant for studying neuroinflammation, including Alzheimer's disease.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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