ALG-055009

• Target :

  Thyroid hormone receptor (THR)

• Related Pathways :

  Endocrinology/Hormones

• Bioactivity :

  ALG-055009, a thyroid hormone receptor ? (THR-?) agonist, exhibits an EC50 of 0.063 ?M. It has been shown to reduce total cholesterol levels in rats fed a high-fat diet. ALG-055009 is used in the study of fatty liver diseases associated with metabolic dysfunction.

• Smiles :

  O=C1NC(=O)N(N=C1N)C2=CC(Cl)=C(OC3=NNC(=O)C(=C3)C(C)C)C(Cl)=C2

• Molecular Formula :

  C16H14Cl2N6O4

• Molecular Weight :

  425.23

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2542029-03-6