ALG-055009

CAT: 0804-HY-168046-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-168046-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ALG-055009 is a thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.063 μM. In rats on a high-fat diet, ALG-055009 can lower total cholesterol levels. ALG-055009 can be used in studies related to metabolic dysfunction-associated fatty liver disease[1].
CAS Number
[2542029-03-6]
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/alg-055009.html
Concentration
10mM
Purity
95.32
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C1=CC(OC2=C(Cl)C=C(N3N=C(C(NC3=O)=O)N)C=C2Cl)=NNC1=O)C
Molecular Formula
C16H14Cl2N6O4
Molecular Weight
425.23
References & Citations
[1]Vandyck K, et al. Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-β) Agonist for the Treatment of MASH. J Med Chem. 2024 Sep 12;67 (17) :14840-14851.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Related Products

CatalogName
HY-177022-01ALG-001075
HY-169993-01ALG-000184
HY-175029ALG-097558
HY-P991095ALG.APV-527
HY-P81520-01PDCD6/ALG-2 Antibody (YA1265, Rabbit)
HY-P10760PhAc-ALGP-Dox
HY-P88649ALG2 Antibody (YA8333, Mouse)
HY-RS00595ALG6 Human Pre-designed siRNA Set A
HY-RS28622Alg6 Rat Pre-designed siRNA Set A
HY-RS27811Alg2 Rat Pre-designed siRNA Set A

Alternative Products

CatalogName
C03579-01ALG-055009
A24211-5ALG-055009 5mg
A24211-50ALG-055009 50mg
A24211-10ALG-055009 10mg
A24211-100ALG-055009 100mg
MF-0062494-01ALG-097558
MF-0062492-01ALG-001075
MF-0062491-01ALG-000184
abx831061-01Alg-991
591656Alg-991 (Urushiol)

Popular Products