ALG-055009
CAT:
804-HY-168046-03
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ALG-055009
- CAS Number: 2542029-03-6
- UNSPSC Description: ALG-055009 is a thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.063 μM. In rats on a high-fat diet, ALG-055009 can lower total cholesterol levels. ALG-055009 can be used in studies related to metabolic dysfunction-associated fatty liver disease[1].
- Target Antigen: Thyroid Hormone Receptor
- Type: Reference compound
- Related Pathways: Vitamin D Related/Nuclear Receptor
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/alg-055009.html
- Smiles: CC(C1=CC(OC2=C(Cl)C=C(N3N=C(C(NC3=O)=O)N)C=C2Cl)=NNC1=O)C
- Molecular Weight: 425.23
- References & Citations: [1]Vandyck K, et al. Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-β) Agonist for the Treatment of MASH. J Med Chem. 2024 Sep 12;67(17):14840-14851.
- Shipping Conditions: Room temperature
- Clinical Information: Phase 2