ALG-001075

• Target :

  HBV

• Related Pathways :

  Microbiology/Virology

• Bioactivity :

  ALG-001075, a capsid assembly modulator (CAM), is an orally active inhibitor of HBV. It effectively suppresses HBV DNA production in primary human hepatocytes and significantly reduces extracellular levels of HBsAg/HBeAg and intracellular HBV RNA. In AAV-HBV mouse models, ALG-001075 notably decreases HBV DNA levels. It can be utilized in research related to chronic hepatitis B (CHB) .

• Smiles :

  N#CC1=CC(=CC=C1F)NC(=O)C2=C(C(C(=O)C(=O)NC3(C#C)COC3)=C(N2C)C)C

• Molecular Formula :

  C22H19FN4O4

• Molecular Weight :

  422.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2495324-66-6