PhAc-ALGP-Dox

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  PhAc-ALGP-Dox is a peptide-drug conjugate and a novel antitumor prodrug. It exhibits a range of IC50 values from 311 nM to 34.25 ?M against TNBC (E0771), normal mouse epithelium (HC-11), human TNBC (MDA-MB-231 and MDA-MB-468), human colorectal cancer (LS 174T), and normal human epithelium (HME-1) cells.

• Smiles:

  OC=1C2=C([C@@H](O[C@H]3C[C@H](NC(=O)[C@H]4N(C(CNC([C@@H](NC([C@@H](NC(CP(=O)(O)O)=O)C)=O)CC(C)C)=O)=O)CCC4)[C@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C5C1C(=O)C=6C(C5=O)=C(OC)C=CC6

• Molecular Formula:

  C45H58N5O19P

• Molecular Weight:

  1003.94

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1616592-31-4