PhAc-ALGP-Dox

CAT: 0931-TP2980-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2980-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1616592-31-4
Target
Others
Related Pathways
Others
Bioactivity
PhAc-ALGP-Dox is a peptide-drug conjugate and a novel antitumor prodrug. It exhibits a range of IC50 values from 311 nM to 34.25 ?M against TNBC (E0771), normal mouse epithelium (HC-11), human TNBC (MDA-MB-231 and MDA-MB-468), human colorectal cancer (LS 174T), and normal human epithelium (HME-1) cells.
Smiles
OC=1C2=C([C@@H](O[C@H]3C[C@H](NC(=O)[C@H]4N(C(CNC([C@@H](NC([C@@H](NC(CP(=O)(O)O)=O)C)=O)CC(C)C)=O)=O)CCC4)[C@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C5C1C(=O)C=6C(C5=O)=C(OC)C=CC6
Molecular Formula
C45H58N5O19P
Molecular Weight
1003.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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