COX-2-IN-48

CAT: 0931-T200441-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T200441-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

NF-κB, COX, NO Synthase

Related Pathways

NF-κB, Neuroscience, Immunology/Inflammation

Bioactivity

COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19238938-01	COX-2-IN-48
311865-01	Cox-2
GTR19206710-01	COX-2-IN-2
BA5932-10	COX-2-IN-6
HY-175637	COX-2-IN-57
HY-171992-01	COX-2-IN-55
HY-153762-01	COX-2-IN-32
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HY-147809	COX-2-IN-20

COX-2-IN-48

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