COX-2-IN-48

CAT: 0013-GTR19238938-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19238938-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

COX-2-IN-48 (5-25) is a potent and selective COX-2 inhibitor (IC50 = 51.7 nM) with demonstrated anti-inflammatory and analgesic activity in rodent models. Its mechanism involves suppressing the NF-κB pathway, thereby inhibiting IκB degradation, p65 nuclear translocation, and downstream expression of COX-2 and iNOS.

Field of Research

Immunology & Inflammation, Neuroscience, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

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