STAT3-IN-31

• Target:

  STAT

• Related Pathways:

  Stem Cells|||JAK/STAT signaling

• Bioactivity:

  STAT3-IN-31 (compound K2071), derived from STATtic, acts as an inhibitor of both STAT3 and mitotic processes. This compound interrupts mitotic progression and impacts the formation of the mitotic spindle. Additionally, STAT3-IN-31 hampers migration in glioblastoma cells, suppresses cellular proliferation within tumor spheroids, induces senescence in glioblastoma, and inhibits the growth of Temozolomide-resistant cells while reducing the secretion of the pro-inflammatory cytokine monocyte chemoattractant protein (MCP-1) .

• Molecular Formula:

  C16H15NO3S

• Molecular Weight:

  301.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C