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CGAMP disodium

CAT: 0931-T13606L-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0931-T13606L-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2407516-83-8
Target
Others, Endogenous Metabolite, STING
Related Pathways
Metabolism, Others, Immunology/Inflammation
Bioactivity
CGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I interferons and other immune mediators by activating interferon gene stimulator (STING) . cGAMP disodium is a potent sublingual immune adjuvant that enables better immune function (serum anti-PA neutralization and airway secretions anti-PA SIgA response) .
Smiles
O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP(O)(OC[C@]3([H])[C@@]([C@H]([C@H](N4C5=NC=NC(N)=C5N=C4)O3)O)([H])OP(O)(OC2)=O)=O)N6C7=C(C(N=C(N7)N)=O)N=C6.[Na].[Na]
Molecular Formula
C20H24N10O13P2.2Na
Molecular Weight
720.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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