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Recombinant human PDCD4 protein

CAT: 0112-ATGP3833-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3833-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDCD4, also known as Programmed cell death 4, encodes a tumor suppressor protein whose expression is lost in progressed carcinomas of lung, breast, colon, and prostate. The expression of PDCD4 gene is strongly induced during apoptosis in a number of cell types. It is modulated by cytokines in natural killer and T cells. Recombinant human PDCD4, was expressed in E. coli and purified by conventional chromatography techniques.
Product Name Alternative
Programmed cell death protein 4 isoform 1, H731
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
51.7 kDa (469aa)
Additionnal Information
PDCD4, Programmed cell death protein 4 isoform 1, H731, ATGP3833-10 µg, ATGP3833-20 µg, ATGP3833-50 µg, ATGP3833-100 µg, ATGP3833-250 µg, ATGP3833-500 µg, ATGP3833-1 mg, ATGP3833-10, ATGP3833-20, ATGP3833-50, ATGP3833-100, ATGP3833-250, ATGP3833-500, ATGP3833-1
References & Citations
Yoshinaga H., et al. (1999) Pathol lnt. 49 (12) :1067-77; ; Palamarchuk A., et al. (2005) Cancer Res. 65 (24) :11282-6.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_055271
Uniprot Accession Number
Q53EL6
Species
Human
AA Sequence
MDVENEQILN VNPADPDNLS DSLFSGDEEN AGTEEIKNEI NGNWISASSI NEARINAKAK RRLRKNSSRD SGRGDSVSDS GSDALRSGLT VPTSPKGRLL DRRSRSGKGR GLPKKGGAGG KGVWGTPGQV YDVEEVDVKD PNYDDDQENC VYETVVLPLD ERAFEKTLTP IIQEYFEHGD TNEVAEMLRD LNLGEMKSGV PVLAVSLALE GKASHREMTS KLLSDLCGTV MSTTDVEKSF DKLLKDLPEL ALDTPRAPQL VGQFIARAVG DGILCNTYID SYKGTVDCVQ ARAALDKATV LLSMSKGGKR KDSVWGSGGG QQSVNHLVKE IDMLLKEYLL SGDISEAEHC LKELEVPHFH HELVYEAIIM VLESTGESTF KMILDLLKSL WKSSTITVDQ MKRGYERIYN EIPDINLDVP HSYSVLERFV EECFQAGIIS KQLRDLCPSR GRKRFVSEGD GGRLKPESY

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