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PDCD4 Recombinant Protein

CAT: 0223-92-115Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-115Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.
CAS Number
9000-83-3
NCBI Gene ID
27250
Swiss Prot
Q53EL6
Accession Number
Q53EL6
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Signal Transduction, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
17 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Programmed cell death 4 (neoplastic transformation inhibitor)
NCBI Organism
Homo sapiens
Other Product Names
Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731
Species
Human
Physical Properties
Lyophilized

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