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Recombinant human PDCD6 protein

CAT: 0112-ATGP0978-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0978-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Programmed cell death 6, also known as PDCD6, is calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Recombinant human PDCD6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Name Alternative
Programmed cell death protein 6, Programmed cell death protein 6, ALG-2, PEF1B, programmed cell death 6, Apoptosis-linked gene 2 protein, FLJ46208, MGC111017, apoptosis-linked gene-2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
24.0 kDa (211aa) confirmed by MALDI-TOF
Additionnal Information
PDCD6, Programmed cell death protein 6, Programmed cell death protein 6, ALG-2, PEF1B, programmed cell death 6, Apoptosis-linked gene 2 protein, FLJ46208, MGC111017, apoptosis-linked gene-2, ATGP0978-10 µg, ATGP0978-20 µg, ATGP0978-50 µg, ATGP0978-100 µg, ATGP0978-250 µg, ATGP0978-500 µg, ATGP0978-1 mg, ATGP0978-10, ATGP0978-20, ATGP0978-50, ATGP0978-100, ATGP0978-250, ATGP0978-500, ATGP0978-1
References & Citations
Okumura M., et al. (2009) Biochem. Biophys. Res. Commun. 386:237-241.; ; Suzuki H., et al. (2008), Structure 16:1562-1573
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 40% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_037364
Uniprot Accession Number
O75340
Species
Human
AA Sequence
MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V

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