Compound 401

CAT: 0804-HY-19341-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-19341-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro.
CAS Number
[168425-64-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA-PK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Compound-401.html
Purity
99.97
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C1C=C(N2CCOCC2)N=C3N1C=CC4=C3C=CC=C4
Molecular Formula
C16H15N3O2
Molecular Weight
281.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Ballou LM, et al. Inhibition of mammalian target of rapamycin signaling by 2- (morpholin-1-yl) pyrimido[2,1-alpha]isoquinolin-4-one. J Biol Chem. 2007 Aug 17;282 (33) :24463-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-13022A-01CC-401
HY-109804-01CORM-401
HY-108238BSI-401
HY-19554MM-401
HY-P991542GBR-401
HY-163737-01ST-401
HY-131181-01LEI-401
HY-178230EVT‑401
HY-12312-01TCS 401
HY-12537-01Peptide 401

Alternative Products

CatalogName
ALX-550-516-M025Compound A
MBS3613444-01Compound W
MBS3609932-01Compound 3A
M24081-01Compound 3344
M33152-01Compound TCFN92660
M39818-01Compound K
255023-01Compound 401
MBS3613756-01Compound 23
PDK0255-01Compound PDK0255
T19204Compound 2

Popular Products