HYNIC-iPSMA (TFA)

• Description :

  HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen) . HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA) . 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity[1]. HYNIC-iPSMA TFA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

• UNSPSC :

  12352209

• Target :

  PSMA; Radionuclide-Drug Conjugates (RDCs)

• Type :

  Peptides

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hynic-ipsma-tfa.html

• Purity :

  98.05

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  OC(C(F)(F)F)=O.O=C(C(C=C/1)=CNC1=N\N)N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC2=CC3=C(C=CC=C3)C=C2

• Molecular Formula :

  C33H38F3N7O11

• Molecular Weight :

  765.69

• References & Citations :

  [1]Ferro-Flores G, et al. Clinical translation of a PSMA inhibitor for 99mTc-based SPECT. Nucl Med Biol. 2017 May;48:36-44.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [2375849-11-7]