HYNIC-iPSMA

• Description :

  HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen) . HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA) . 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity[1]. HYNIC-iPSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

• UNSPSC :

  12352209

• Target :

  PSMA; Radionuclide-Drug Conjugates (RDCs)

• Type :

  Peptides

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hynic-ipsma.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=C(N=C1)NN)N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC2=CC3=C(C=CC=C3)C=C2

• Molecular Formula :

  C31H37N7O9

• Molecular Weight :

  651.67

• References & Citations :

  [1]Ferro-Flores G, et al. Clinical translation of a PSMA inhibitor for 99mTc-based SPECT. Nucl Med Biol. 2017 May;48:36-44.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [2192215-74-8]