MHI-148

• Description :

  MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1].

• CAS Number :

  [172971-76-5]

• Product Name Alternative :

  IR-808

• UNSPSC :

  12171500

• Hazard Statement :

  H319

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mhi-148.html

• Purity :

  98.39

• Solubility :

  DMSO : 20.83 mg/mL (ultrasonic)

• Smiles :

  CC(C1=CC=CC=C1N/2CCCCCC(O)=O)(C)C2=C/C=C3CCCC(/C=C/C4=[N+](CCCCCC(O)=O)C5=CC=CC=C5C4(C)C)=C\3Cl.[Br-]

• Molecular Formula :

  C42H52BrClN2O4

• Molecular Weight :

  764.23

• Precautions :

  H319

• References & Citations :

  [1]Athira Raveendran, et al. Heptamethine Cyanine Dye MHI-148-Mediated Drug Delivery System to Enhance the Anticancer Efficiency of Paclitaxel. Int J Nanomedicine. 2021 Oct 21;16:7169-7180.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported