SAAP 148

• Description :

  SAAP 148 is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC50 of 0.8-12.8 μM[1].

• UNSPSC :

  12352209

• Target :

  Bacterial

• Type :

  Peptides

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/saap-148.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](CC1=CNC2=C1C=CC=C2)C(N[C@@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](C(N[C@@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CNC5=C4C=CC=C5)C(N[C@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](CCCCN)C(N6[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)CCC6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)=O)=O)=O)C

• Molecular Formula :

  C157H261N49O27

• Molecular Weight :

  3267.06

• References & Citations :

  [1]de Breij A, et al., The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms. Sci Transl Med. 2018 Jan 10;10 (423) :eaan4044.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported