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Ceritinib dihydrochloride

CAT: 0957-S4967-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S4967-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.
CAS Number
1380575-43-8
Synonyms
Zykadia, LDK378 dihydrochloride
Target
ALK
Activity
Protein Tyrosine Kinase
Molecular Formula
C28H38Cl3N5O3S
Storage Conditions
3 years -20°C powder

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