Ceritinib

CAT: 0931-MF-0013258-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013258-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1032900-25-6
Target
ALK|||Serine Protease|||IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Proteases/Proteasome
Purity
>99.99%
Bioactivity
Ceritinib (LDK378) is an ALK tyrosine kinase inhibitor (IC50=200 pM) with selective, ATP-competitive, and oral activity. Ceritinib also inhibits IGF-1R, InsR, and STK22D (IC50=8/7/23 nM) . Ceritinib has antitumor activity.
Smiles
N(C1=C(OC(C)C)C=C(C(C)=C1)C2CCNCC2)C=3N=C(NC4=C(S(C(C)C)(=O)=O)C=CC=C4)C(Cl)=CN3
Molecular Formula
C28H36ClN5O3S
Molecular Weight
558.14
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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