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Ceritinib

CAT: 0957-S7083-5mgSize: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7083-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1032900-25-6
Synonyms
LDK378
Target
ALK
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (C=C1C2CCNCC2) OC (C) C) NC3=NC=C (C (=N3) NC4=CC=CC=C4S (=O) (=O) C (C) C) Cl
Molecular Formula
C28H36ClN5O3S
Additionnal Information
Ceritinib is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays. Ceritinib (LDK378) also inhibits IGF-1R, InsR, STK22D and FLT3 with IC50 of 8 nM, 7 nM, 23 nM and 60 nM, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent

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MBS576681LDK378(Ceritinib)
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