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Virginiamycin Complex

CAT: 0804-HY-112665-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112665-01Size:5 mg
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Description
Virginiamycin Complex (Streptogramin) is an antibiotic containing two streptogramins, virginiamycin M (VM) and virginiamycin S (VS), which are produced by S. virginiae. As a complex, these two antibiotics in Virginiamycin Complex act synergistically. The action of VM is persistent and catalytic, and it can alter the affinity of ribosomes for VS. Virginiamycin Complex irreversibly inhibits protein synthesis in bacteria and has antibacterial activity[1].
CAS Number
11006-76-1
Product Name Alternative
Streptogramin; Mikamycin; RP 7293
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/virginiamycin-complex.html
Purity
89.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1CCN([C@@]([H])(C1)C(N[C@H](C(O[C@@H]([C@@H](C(N[C@@H](C(N2CCC3)=O)CC)=O)NC(C4=NC=CC=C4O)=O)C)=O)C5=CC=CC=C5)=O)C([C@H](CC6=CC=CC=C6)N(C([C@@]23[H])=O)C)=O.O=C(NC/C=C\C(C)=C\[C@H](C7)O)/C=C/[C@H]([C@H](OC(C8=CCCN8C(C9=COC(CC7=O)=N9)=O)=O)C(C)C)C
Molecular Formula
C71H84N10O17
Molecular Weight
1349.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Parfait R, Cocito C. Lasting damage to bacterial ribosomes by reversibly bound virginiamycin M. Proc Natl Acad Sci U S A. 1980 Sep;77 (9) :5492-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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