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Virginiamycin S1

CAT: 0804-HY-N6680-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6680-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections[1][2].
CAS Number
23152-29-6
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/virginiamycin-s1.html
Purity
99.13
Solubility
10 mM in DMSO
Smiles
O=C1N2[C@](CC(CC2)=O)([H])C(N[C@@H](C3=CC=CC=C3)C(O[C@@H]([C@H](NC(C4=C(C=CC=N4)O)=O)C(N[C@H](CC)C(N5[C@](CCC5)([H])C(N(C)[C@H]1CC6=CC=CC=C6)=O)=O)=O)C)=O)=O
Molecular Formula
C43H49N7O10
Molecular Weight
823.89
References & Citations
[1]Ningsih F, et al. VisG is essential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine. Microbiology. 2011 Nov;157 (Pt 11) :3213-20.|[2]Ge B, et al. Purification and characterization of virginiamycin M1 reductase from Streptomyces virginiae. Sci Rep. 2017 Sep 8;7 (1) :11017.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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