Complex III-IN-2

• Description :

  Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor. Complex III-IN-2 shows antifungal activity with an EC50 of 29.98 mg/L and 29.31 mg/L against sclerotinia sclerotiorum and R. solani, respectively[1].

• UNSPSC :

  12352005

• Target :

  Fungal; Mitochondrial Metabolism

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/complex-iii-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(C1=CC=C(Cl)N=C1)(NC/C=C(C)/CC/C=C(C)\C)=O

• Molecular Formula :

  C15H21ClN2O2S

• Molecular Weight :

  328.86

• References & Citations :

  [1]Song, X., et al. Synthesis, antifungal activity, and molecular dynamics study of novel geranyl aromatic sulfonamide compounds as potential complex III inhibitors. Med Chem Res 31, 628–642 (2022) .

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported