Complex III-IN-2

• UNSPSC Description:

  Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor. Complex III-IN-2 shows antifungal activity with an EC50 of 29.98 mg/L and 29.31 mg/L against sclerotinia sclerotiorum and R. solani, respectively[1].

• Target Antigen:

  Fungal; Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/complex-iii-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(Cl)N=C1)(NC/C=C(C)/CC/C=C(C)\C)=O

• Molecular Weight:

  328.86

• References & Citations:

  [1]Song, X., et al. Synthesis, antifungal activity, and molecular dynamics study of novel geranyl aromatic sulfonamide compounds as potential complex III inhibitors. Med Chem Res 31, 628–642 (2022).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported