24 (S) -Hydroxycholesterol

CAT: 0498-bs-82183C-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0498-bs-82183C-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

24 (S) -Hydroxycholesterol is an important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain.1 It is an endogenous agonist of the nuclear receptor LXR.2 It has been shown to induce cell death in neuroblastoma cells3, possibly via a necroptosis pathway4. 24 (S) -Hydroxycholesterol has also been found to be a high affinity ligand for RORα and RORγ (Ki = 25 nM) .5 24 (S) -Hydroxycholesterol levels are elevated in the cerebral spinal fluids of patients with neurogenerative diseases suggesting possible clinical applications.6,7 It was also able to reduce Aβ production and increase ER-resident immature amyloid precursor protein (APP) levels in human neuroblastoma SH-Sy5Y cells and CHO cells via inhibition of intracellular amyloid precursor protein trafficking.7

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

Related Products

Catalog	Name
bs-82906C-01	20 (S) -Hydroxycholesterol
bs-82902C-01	27-Hydroxycholesterol
bs-82904C-01	7alpha-Hydroxycholesterol
bs-82905C-01	25-Hydroxycholesterol
bs-82203C-01	MRL-24
bs-82182C-01	24,25-Epoxycholesterol
bs-75850C-01	S-Adenosylmethionine
bs-75823C-01	S-BAIBA
bs-75229C-01	(S) - (+) -Camptothecin
bs-75737C-01	(S) - (+) -Ascochin

Alternative Products

Catalog	Name
TQ0274-01	27-Hydroxycholesterol
B2017926	7β-Hydroxycholesterol
TRC-H703710-50MG	17alpha-Hydroxycholesterol
abx283033-01	7a-Hydroxycholesterol
BUP06234-01	25-Hydroxycholesterol
TRC-H918040-10MG	24-Hydroxycholesterol
M31374-01	7Beta-Hydroxycholesterol
TBW01446	7alpha-Hydroxycholesterol
HY-124265-01	4β-Hydroxycholesterol
H9040-01	Hydroxycholesterol, 20a-

24 (S) -Hydroxycholesterol

Related Products

Alternative Products

Popular Products