BMS-986242

• Description:

  BMS-986242 is an orally active, potent and selective indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor. BMS-986242 can be used for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  Indoleamine 2,3-Dioxygenase (IDO)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bms-986242.html

• Purity:

  98.85

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  FC1=CC2=C(C=C1)N=CC=C2[C@H]3CC[C@@](CC3)([H])[C@@H](C)NC(C4=CC=C(C=C4)Cl)=O

• Molecular Formula:

  C24H24ClFN2O

• Molecular Weight:

  410.91

• References & Citations:

  [1]Cherney EC, et al. Discovery and Preclinical Evaluation of BMS-986242, a Potent, Selective Inhibitor of Indoleamine-2,3-dioxygenase 1. ACS Med Chem Lett. 2021;12 (2) :288-294. Published 2021 Jan 28.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  IDO1

• CAS Number:

  [1923844-48-7]