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CK1-IN-2

CAT: 0804-HY-153866-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153866-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].
CAS Number
1383376-92-8
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck1-in-2.html
Purity
99.54
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1OCC2=NC=CC(C3=CN(C)N=C3C4=CC=C(F)C=C4)=C12
Molecular Formula
C17H12FN3O2
Molecular Weight
309.29
References & Citations
[1]Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1

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